50 yr old Pancytopenia


A 50 YR OLD FEMALE WITH PANCYTOPENIA 

Greetings to one and all who are currently reading my blog.  This is Jasmisri,eighth semester medical student

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A 50 year old female farmer by occupation presented to the OPD with 

CHIEF COMPLAINTS:

generalised weakness since 1 year
loss of appetite since 1 year
hematuria since 2 days 
dizziness since 6 months 
sob ( grade 2) since 6 months 
fever since 1 week
itching on right side of neck since 1 month

HISTORY OF PRESENTING ILLNESS 

Patient was apparently asymptomatic 2 years back then she developed swelling of left lower limb associated with pain and then swelling progressed to whole body due to which she got admitted to Osmania and was treated after which the swelling subsided. Patient was doing fine till 1 year of that event but then gradually developed generalised weakness, easy fatigability, loss of appetite,weight loss, sob ( grade 2-3) not associated with cough,cold or palpitations.

She has pruritus that also began with an inflammatory rash in her neck a month back that currently appears as a post inflammatory hyperpigmentation with a nodular appearance.

She has fever which is intermittent, low grade not associated with chills and rigors 

She also has Hematuria for which she went to local hospital where she found to have Anemia for which she was transfused 5 units of blood in a span of 20 days and was discharged. 
She was doing fine.

Since 6 months patient is experiencing similar complaints and went to hospital where she was found to have Anemia and got transfused 2 units of blood and came here as they were unsatisfied with the treatment there . She was admitted on Saturday July 08 

PAST HISTORY:

Not a known case of HTN, DM 2 , CVA, CAD, TB , EPILEPSY ETC 

She underwent hysterectomy surgery at the age 36 years after the third childbirth.

PERSONAL HISTORY: 

mother of 3 children ( 2 sons and 1 daughter) 
Diet - mixed 
Appetite- decreased since 1 year
Bowel and bladder- regular 
Sleep-adequate
Allergies - No
 
MENSTRUAL HISTORY:

Menarche - 13 years age 
Past - A Regular cycle 5/30 
Present - hysterectomy done at the age of 36 yrs 

DAILY ROUTINE :

She wakes up at 5 o'clock and does her daily activities and then she prepares for breakfast and has breakfast at 7 o'clock and then goes for work and at 12 o'clock she has her lunch near the field and in the evening she gets home bt 7 o'clock and prepares for dinner, eats it and then goes to bed at 9-10 pm.

After symptoms:
She is not going to any work since 1 and half year she stays at home and takes rest.

GENERAL EXAMINATION:

Patient is concious , coherent, cooperative and l well oriented to time, place and person.
Poorly built and poorly nourished 
Patient is examined in a well lit room after taking consent with adequate exposure.

Pallor -present 
Icterus - positive 
Cyanosis - negative
Kolinychia - negative 
Clubbing - negative 
Generalised lympadenopathy - negative 
Edema - negative











VITALS:

BP- 90/60mmhg 
PR- 84bpm 
RR- 16 cpm

SYSTEMIC EXAMINATION 

Rs - BAE +ve , NVBS
CVS - S1 S2 heard , no murmurs 
CNS - NFND
P/A - spleenomegaly 
Size- 17.5 * 15 cms
Surface - smooth 
Consistency - firm
Borders- rounded borders
Spo2 - 98% at RA
Temp- afebrile 


PROVISIONAL DIAGNOSIS

PANCYTOPENIA UNDER EVALUATION 
? AKI ( pre renal) 
Denovo HBSAG positive 

INVESTIGATIONS:-















TREATMENT :

Tab.dolo 650mg po/sos
Sup.aristozyme 10ml po/tid 
Tab.orofer XT po/OD 
Temp monitoring 4th hrly 
Vitals monitoring 4th hrly  


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